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??,MD, PhD
????????????????????????????????10??????????????????? ??1997?????????????????,?2000?????????,?????20??????(NDAs)??100????????? ?(IND)???????????????,??????Westat?????, ??8????/?????????;???????????????;??????????????????1992-1994??????????? ????,??????????????/????????,??????????????????????????????JAMA?AJPH? Controlled Clinical Trials?NEJM?,???30?????????????????????????????????????????